BioSci 98A/B/C/D/E/F


Annexin XII Hexamer

 

Hartmut "Hudel" Luecke
Department of Molecular Biology & Biochemistry
Email: hudel@uci.edu
Office Hours:  Make appointment via email - make sure you have "bio98" in the subject line!

Note: The format below is for the M/W/F-50-minute-lectures version, in 98C/F we will use the T/Th-80-minute-lecture format. Please ignore Date and Day-of-the-Week information below, we will cover these 13 50-minute lectures in 9 80-minute lectures. The midterm is Friday, Feb 6, 2015, in-class, covering all lectures (ppts 1-13).

 

 


 

Lecture #
Date
Day of the Week
Topic
Slides (.ppt)
Slides (.pdf)

Reading

Lehninger 6th

  Reading Assignment (Stryer) Problems (Stryer) Reading Assignment (Horton) Problems (Horton)
1
Non-covalent forces and water

Ch 2

45-58

  2.2-2.4 Ch 2: 2, 5, 6, 8 2.1-2.6 Ch 2: 1, 2, 3
2
Acid-base equilibria, pH and buffers

Ch 2

58-74

  2.2 & 2.5 Ch 2: 10, 12, 14, 18 2.7-2.10 Ch 2: 4, 6, 7, 8
3
Amino acids and the peptide bond

Ch 3

75-88

  3.1-3.3; 4.1 Ch 3: 3, 4, 5, 10, 13 3.1-3.2 & 3.4-3.5 Ch 3: 8, 10
4
Purification and characterization of proteins

Ch 3

89-97

  5.2 Ch 5: 2, 7, 9 & purification 3.6-3.7  
5
Protein sequencing and protein identification

Ch 3

98-108

  5.2 & 5.4 Ch 5: 2a-f, 6, 18, 19 3.7-3.11 Ch 3: 9, 13
6
Three dimensional structure of proteins Ch 4   4.1-4.5 Ch 4: 2, 4, 7, 20, 21 4.1-4.10 Ch 4: 1, 3, 4, 8
7
Myoglobin & hemoglobin

Ch 5

157-179

  9.1-9.5 & Ch 7 pgs 114-117 Ch 9: 2, 4, 7 , 20, 21 4.12-4.13, 5.10C Ch 4: 12, 13, 14
8
Enzymes I Ch 6   6.1 & 6.4; Ch 16 pgs 272-274; 8.3

Ch 6: 6, 10; Ch 8: 10, 11

5.2, 6.1-6.3, 6.5, 6.7

Ch 6: 1, 6, 7, 10
9
Enzymes II Ch 6   7.1-2; 8.2 (competitive inhibition only) Ch 7: 3, 6, 7, 11 (not i or h); Ch 8 5a, 6 5.3-5.5, 5.7A, 5.8 Ch 5: 2, 5, 6, 7
10
Enzymes III Ch 6   7.3; Ch 13 pgs 219-220 & 223-224; Ch16.4 pgs 287-290 Ch 7: 17, 18, 22

5.9&5.11, 10.2B&C

Ch 5: 13

Ch 10: 1, 3

11
Carbohydrates Ch 7   10.1-2 Ch 10: 3a-g, 8, 13 8.1-8.2, 8.5A&B, 8.6A&B Ch 8: 5, 7
12
Lipids Ch 10   11.1-11.3 Ch 11: 2, 3, 9, 18, 19 9.1-9.6, 9.8B, Box9.4 Ch 9: 1, 2ab
13
Bioenergetics Ch 13   6.3; 15.1-2 Ch 6: 18, 22; Ch 15 9, 11, 14 10.5-10.7 Ch 10: 4
MT
Fri, Feb 6
Midterm (all lectures, in-class)
Lectures 1-13
           

Score breakdown: up to 6% for participation in discussion sections (1% each), 44-50% for my midterm. The balance will be for Dr. Hu's section  (50%).

 

Discussion Section set 1 (Week of Jan 12): Worksheet1.pdf (TA: Alborz Karimzadeh ; Office hours: Tuesdays 4:30-5:30 pm in 1246 McGaugh Hall) Worksheet1_Solutions.ppt

Discussion Section set 2 (Week of Jan 26): Worksheet2.pdf (TA: Rutav Mehta ; Office hours: Thursdays from 10.30-11.30 am in 2419 McGaugh Hall) Worksheet2_Solutions.ppt

Discussion Section set 3 (Week of Feb 2): Worksheet3.pdf (TA: Luke Nelson ; Office hours: Thursdays 1-2 pm outside the Starbucks in the MedEd building on the Med School side of campus) Worksheet3_Solutions.pdf

 

FREE? Biological Sciences Peer Tutoring Program

Allen Khai (Khaia@uci.edu)
Nobel Nguyen (nobeln@uci.edu)

 

LARC Tutoring Program

Allen Tran (AVTRAN1@uci.edu)
John Ngo (jtngo2@uci.edu)

 

Midterm (sorry, not the one for this quarter) with key:  midterm_WQ11_key.pdf

 

Lehninger edition 6 (if it ever arrives - yeah, I got mine on Jan 8!).

Older textbook: BIOCHEMISTRY A Short Course, by Tymoczko • Berg • Stryer (2nd edition, 2011); ISBN 1-4292-8360-2.

Older textbook: PRINCIPLES OF BIOCHEMISTRY by Horton, Moran, Ochs, Rawn, Scrimgeour & Perry (4th edition, 2005); ISBN 0131453068.

 

Terms you should know: List of terms

More practice midterms from prior years without answers:  Mid06   Mid07   Mid08

More practice midterms from prior years with keys:  MidKey06   MidKey07   MidKey07b   MidKey08  MidKey09

(C) 1998-2015, unauthorized or for-profit use strictly prohibited. Hartmut Luecke, MB&B, UCI (Jan 2015) http://urei.bio.uci.edu/~hudel/bs98a